The science behind Auregen

 

Auregen is the only product in the world that uses revolutionary Gold Nanocarrier technology to transport D-Ribose across the cellular membrane and into the mitochondria to repair oxidative stress and repair and balance Andenosine Triphosphate (ATP) the bioenergetic compound.

 

Auregen NanoGold/D-Ribose powder is a gold nanoparticle (GNPs) based super anti-oxidant and anti-bacterial supplement that is functionalized with D-Ribose. Auregen is all natural and there is no other ingredient or component except for NanoGold and D-Ribose.

 

 

Improve heart health and eliminate chronic fatigue

Cellular damage accumulation is one of the most accepted causes of aging and age related diseases Damage accumulation is thought to be driven, among others, by oxidative stress. This condition results in an excess attack of oxidants on biomolecules, which lead to damage accumulation over time and contribute to the functional involution of cells, tissues and organisms. If oxidative stress persists, cellular senescence is a likely outcome and an important hallmark of aging. A multitude of dietary supplement are available to attempt to cure damage accumulation and other cellular issues. However, according to research, typical dietary supplements cannot efficiently cross the cellular membrane because of the large size of their molecules unless they are synthesized onto the surface of Gold Nanoparticle (GNP) nanocarriors.

 

Auregen’s GNP structure is uniquely designed to remedy both of the problem statements. Auregen is the only product in the world that uses revolutionary Gold Nanocarrier technology to transport D-Ribose across the cellular membrane and into the mitochondria to repair oxidative stress and repair and balance Andenosine Triphosphate (ATP) the bioenergetic compound.

Auregen NanoGold/D-Ribose powder is a gold nanoparticle (GNPs) based super anti-oxidant and anti-bacterial supplement that is functionalized with D-Ribose. Auregen is all natural and there is no other ingredient or component except for NanoGold and D-Ribose.

 

 

NanoGold Transport Technology

The GNPs in Auregen act like an armored transport vehicle loaded with a payload of D-Ribose. GNPs, the most effective natural anti-oxidants, cross the cellular membrane and instantly begin using their electron arsenal to repair oxidative stress and bacterial caused inflammation. By enzymatic action, the GNPs then release D-Ribose. D-Ribose immediately begins to repair stagnant ATP the bioenergetic molecule required for the fundamental biological processes that make life possible. With oxidative stress diminished and the biological processes working more efficiently. One’s body is able to effectively make use of the D-Ribose to balance out ATP production.

D-Ribose, a pentose sugar, is the only sugar used by the body to regulate the metabolism of nucleotides. D-Ribose is not used to fuel energy recycling like the so called “bad” sugars. It is not metabolized via glycolysis, the biochemical pathway in which “bad” sugar is converted into energy. Instead, it drives the process of energy recovery by actually making the ATP bioenergetic compounds and keeping them in the cell. Only Ribose performs this very vital cellular function.

 

 

Auregen D-Ribose Benefits

- Treat Heart Disease and Improve Heart Health

- Helps with Fibromyalgia and Chronic Fatigue Syndrome

- Replenishes Energy Reserves

- Improves Muscular Strength

- Help with Restless Leg Syndrome

- Improve Symptoms of Adenylosuccinase Deficiency

- Treat Myoadenylate Deaminase Deficiency

- Protect the Kidneys

- Improve Weight Loss

- Reduce Testicular Toxicity Caused by Aluminum

 

 

What is D-Ribose

D-Ribose is a unique pentose “good” sugar, not a “bad” sugar. D-Ribose is used in key body structures such as ATP, DNA and RNA. It is not “burned” for energy, as normal sugars are, such as fructose, glucose, or sucrose.

Ribose is the only sugar used by the body to regulate the metabolism of nucleotides. Ribose is not used to fuel energy recycling like the “bad” sugars. Instead, it drives the process of energy recovery by actually making the ATP energy compounds and keeping them in the cell. Only Ribose performs this very vital cellular function.

 

D-ribose is found in every cell in the body. It is not metabolized via glycolysis, the biochemical pathway in which “bad” sugar is converted into energy.

 

In addition to its role in genetics, ribose is a major component of the energy molecule known as ATP (adenosine triphosphate). ATP consists of a base, known as a purine; three phosphate (triphosphate) molecules; and the sugar ribose. Ribose is the only sugar used by the body to help regulate the metabolism of nucleotides—i.e., ATP, ADP (adenosine diphosphate), and AMP (adenosine monophosphate).

During times of metabolic stress or disease, ribose can help restore normal, healthy levels of ATP required for the intricate biochemical and physiological processes that help maintain life.

 

 

Cellular and Cardiovascular Function

The heart is a metabolic machine. On average, it beats approximately 100,000 times per day. This degree of metabolic activity requires a significant energy reserve and the constant recycling and/or production of energy molecules.

 

Cardiovascular disease (CVD) continues to be a leading cause of death worldwide. One of the common factors in CVD is a lack of oxygen (ischemia), which leads to a significant decrease in ATP production and overall heart function. Joanne Ingwall, PhD, of Brigham and Women’s Hospital proposed that a failing heart is energy starved. Ribose helps improve the synthesis of adenine nucleotide reserves, which in turn helps increase ATP production and improves the heart’s tolerance to ischemia.

 

How does ribose accomplish this? ATP recovery depends on increased levels of phosphoribosyl-pyrophosphate (PRPP), which is formed from ribose-5-phosphate by the enzyme ribosephosphate diphosphokinase. Increased levels of PRPP can aid in the production of ATP.

In addition to its major role in ATP synthesis, PRPP is the gatekeeper for maintaining purines inside the cells, helping to ensure a pool of these ATP precursors to support energy recovery. During transient myocardial ischemia, levels of ADP and AMP increase, while their rephosphorylation to ATP decreases significantly. After long periods of ischemia, AMP and ADP are broken down to adenosine, inosine, and other metabolites, which are then cleared from the cell. The loss of purines causes significant metabolic disturbances. If the cells lose purines such as adenine, they cannot resynthesize much-needed ATP. During times of extreme stress—such as heart attack or congestive heart failure (CHF)—purines are lost from heart cells, thereby limiting the heart's ability to generate the ATP needed to regain normal heart function. Ribose quickly forms PRPP, which helps prevent the loss of purines and serves as the driver of ATP synthesis.

 

Studies show that providing daily ribose supplementation helps improve diastolic function, quality of life, and physical function scores in patients with CHF. Ventilatory efficiency is recognized as an important predictor of survival and disease progression among patients with CHF. Ribose has been shown to improve ventilatory efficiency, and demonstrates a subjective improvement in quality of life in CHF patients. Patients given ribose were able to breathe more easily and with greater efficiency. There are no good natural sources of ribose. The body, although capable of making ribose from glucose, does so very slowly and not efficiently enough to support an ailing cardiovascular system. In many cardiovascular conditions, including ischemia, CHF, and cardiomyopathy, supplemental ribose provides a significant benefit by increasing the speed of ATP repletion and enhancing functional recovery after injury in acute and chronic cardiovascular disease.

Energy Metabolism, Exercise Performance

 

In addition to its numerous benefits in cardiovascular health, ribose has been shown to support many other biochemical and physiological functions in the body. A pilot study was completed with 41 patients diagnosed with CFS and/or fibromyalgia. Both conditions are associated with impaired cellular energy metabolism. With ribose supplementation, a significant improvement was seen in the five major areas of assessment: energy, sleep, mental clarity, pain intensity, and well-being in patients receiving ribose.

 

Ribose supplementation has also been shown to support exercise performance and recovery. One study investigated the effect of ribose on skeletal muscle total adenine nucleotide (TAN) concentration following high-intensity exercise (cycle sprints). Following the exercise period, muscle biopsies revealed a significantly greater TAN in the ribose-supplemented group. This suggests ribose may provide an ergogenic effect overtime in high-intensity cycling activity.

 

In a four-week study in recreational male body builders, ribose supplementation was shown to support an increase in strength and muscle endurance, but had no affect on body composition. Supplementation of ribose demonstrates a significant benefit to cellular energy metabolism by limiting the depletion of TANs and supporting ATP resynthesis in muscle tissue, thereby helping to modulate key mechanisms involved in exercise performance.

 

In another study, one week of intense intermittent cycling was sufficient enough to markedly reduce muscle adenine nucleotide levels. Following this intense training, ribose supplementation significantly enhanced the rate of adenine nucleotide resynthesis, most likely by increasing PRPP synthesis. PRPP synthesis is an essential rate limiting factor for ATP resynthesis in skeletal muscle, and may in fact influence exercise performance.

 

 

Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure or prevent disease.  Always consult with your professional health care provider before changing any medication. The information provided herein does not substitute for a face-to-face consultation with your physician, and should not be construed as individual medical advice.

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